Phenomenex Kinetex C18 HPLC Column – 150 × 4.6 mm

Phenomenex Kinetex C18 HPLC Column – 150 × 4.6 mm

The Phenomenex Kinetex C18 is a high-performance HPLC/UHPLC column based on advanced Core-Shell technology. Thanks to the core-shell particles, this column offers high chromatographic efficiency and excellent separation, with capabilities to shorten analysis time, improve resolution, and reduce solvent consumption.

The C18 phase is a versatile reversed-phase stationary phase and is suitable for a wide range of HPLC applications. Kinetex C18 columns are designed to improve existing HPLC methods and can deliver significant performance improvements compared to conventional fully porous columns. Phenomenex positions Kinetex Core-Shell technology for, among other things, higher productivity, better resolution, and reproducible results across different LC systems and laboratories.

The 150 × 4.6 mm version is a widely used analytical column size for HPLC. Phenomenex lists this configuration as, among other things, a suitable dimension for C18 Core-Shell applications. Technical specifications
Specification Value
Brand Phenomenex
Series Kinetex
Type C18
Technology Core-Shell
Application HPLC / UHPLC
Separation mode Reversed Phase
Stationary phase C18
Particle size 2.6 µm*
Pore size 100 Å
Length 150 mm
Inner diameter 4.6 mm
Dimensions 150 × 4.6 mm
Surface area approx. 200 m²/g
Carbon load approx. 12%
pH range approx. 1.5–8.5**
Typical flow at 2.6 µm / 4.6 mm approx. 1.8 mL/min
Typical pressure at 150 mm approx. 5,300 psi
Maximum recommended temperature approx. 60 °C

* The 2.6 µm specification applies to the one referred to here Kinetex C18 version. Phenomenex also supplies Kinetex C18 with other particle sizes, including 1.3, 1.7, and 5 µm.

** The exact pH stability depends on the conditions; Phenomenex states a range of approximately pH 1.5–8.5 under gradient conditions for the standard Kinetex C18.

Key benefits
Core-Shell technology for high chromatographic efficiency.

Improved resolution and peak shape compared to many conventional fully porous columns.

Possibility of shorter analysis times.

Potentially lower solvent consumption.

Suitable for existing HPLC methods and method optimization.

Reproducible performance between different LC systems and laboratories.

Wide applicability for reversed-phase HPLC.

150 × 4.6 mm is a commonly used analytical column configuration. For example, Phenomenex has shown that a Kinetex C18 2.6 µm 150 × 4.6 mm column can offer higher efficiency and shorter analysis time than traditional 5 µm columns with a length of 250 mm.

Dimensions

Column dimensions: 150 mm length × 4.6 mm inner diameter

This refers to the chromatographic column size and not necessarily the total physical length including end fittings.

Suitable for: HPLC, UHPLC, reversed-phase chromatography, analytical laboratories, pharmaceutical analysis, R&D, and method development.