Waters XSelect Premier HSS T3 VanGuard FIT HPLC-column – 2,5 µm, 2,1 × 100 mm

The Waters XSelect Premier HSS T3 VanGuard FIT is a high-performance reversed-phase HPLC/UHPLC column featuring a 2.5 µm C18 phase, designed for the separation of both polar and non-polar compounds.

The HSS T3 phase is a low-coverage C18 phase compatible with mobile phases containing up to 100% aqueous content. This makes the column particularly well-suited for method development involving the separation of both polar and hydrophobic analytes.

XSelect Premier columns utilize MaxPeak High Performance Surface (HPS) technology. This technology is designed to minimize unwanted interactions between analytes and the column surface, resulting in benefits such as improved peak shape, higher reproducibility, and reduced signal intensity loss.

Additionally, this model features the VanGuard FIT column design, which protects the analytical column from contaminants, thereby extending the column’s lifespan. Technical specifications

Specification Value

Brand Waters

Series XSelect Premier

Type HSS T3 VanGuard FIT

Phase HSS T3 C18

Column type Reversed Phase

Particle size 2.5 µm

Column length 100 mm

Inner diameter 2.1 mm

Dimensions 2.1 × 100 mm

Technology MaxPeak High Performance Surface

Protection VanGuard FIT

Mobile phase Suitable for up to 100% aqueous mobile phase

MS bleed Ultra-low

Application HPLC / UHPLC / UPLC

Suitable for Polar and non-polar compounds

Packaging 1 column per pack

Key benefits

HSS T3 low-coverage C18 phase for broad applicability.

Suitable for mobile phases with up to 100% water.

Suitable for both polar and non-polar compounds.

Ultra-low MS bleed; suitable for LC-MS applications.

High separation performance due to 2.5 µm particle size.

Designed for both HPLC and UHPLC.

Easy scalability to UPLC methods.

MaxPeak HPS technology reduces unwanted analyte-surface interactions.

Can contribute to better peak shape and reduced loss of signal intensity.

VanGuard FIT protects the column against contaminants and can extend column lifetime.

Good combination of efficiency, robustness, and throughput.

Applications

The Waters XSelect Premier HSS T3 is particularly suitable for method development and analytical separations involving the analysis of both polar and non-polar compounds. The combination of the C18 HSS T3 phase, low MS bleed, and MaxPeak HPS technology makes the column suitable for applications including HPLC, UHPLC, and LC-MS.

Moreover, the column serves as a practical step towards UPLC methods, as the methods are scalable and transferable.

Dimensions

Column length: 100 mm

Inner diameter: 2.1 mm

Particle size: 2.5 µm

Column dimensions: 2.1 × 100 mm