BMG Labtech CLARIOstar Plus Microplate Reader

The CLARIOstar Plus is a multi-mode microplate reader with advanced LVF Monochromators, highly sensitive filters, and an ultra-fast UV/vis spectrometer. The Enhanced Dynamic Range and automatic focus technologies make manual settings superfluous and detection optimisation easier than ever.

The CLARIOstar Plus comes now with Voyager , BMG LABTECH´s new microplate reader control interface. Designed to remove complexity while maximising flexibility, Voyager makes data acquisition more intuitive than ever.

Detection Modes:

Fluorescence intensity (incl. FRET)

Fluorescence polarization

Luminescence (flash and glow) – incl. BRET

Time-resolved fluorescence

TR-FRET

UV/vis absorbance spectra

Measurement Modes:

Top and bottom reading

Endpoint and kinetic

Sequential multi-excitation

Sequential multi-emission

Spectral scanning (fluorescence, luminescence, absorbance)

Ratiometric measurements

Well scanning

Microplate Formats:

6- to 1536-well plates, user-definable

LVis Plate with 16 low volume microspots (2 μL)

Microplate Carrier:

Robot compatible

Light Sources:

High energy xenon flash lamp

Detectors:

Low-noise photomultiplier tube

CCD spectrometer

Wavelength Selection:

Dual Linear Variable Filter (LVF) Monochromators

Linear Variable Dichroic Mirror

Separates ex & em LVF Monochromators

Spectral Range:

LVF Monochromators

FI: 320 – 740 nm

LUM: 320 – 740 nm

Linear Variable Dichroic

340 – 740 nm

Spectrometer

ABS: 220 – 1000 nm; wavelength precision: ≤ 0.5 nm

Sensitivity:

FI monochromator (top)

< 0.35 pM (< 7 amol/well FITC, 384sv, 20 μL).

FI monochromator (bottom)

< 3.0 pM (< 150 amol/well FITC, 384g, 50 μL).

Dynamic Range: 8 decades in a single measurement.

FP

< 0.5 mP SD at 1 nM FITC (384sv, 20 μL).

HTRF (black and white microplates)

Reader Control Kit (Eu) after 18h (384sv, 20 μL).

Delta F > 880% (High Calibrator).

Delta F > 30% (Low Calibrator).

TRF

< 20 fM europium, 384, 80 μL (<1.6 amol/well).

LUM

< 0.4 pM (< 8 amol/well ATP, 384sv, 20 μL).

Dynamic range: 8 decades in a single measurement.

ABS with spectrometer.

Selectable spectral resolution: 1, 2, 5, and 10 nm.

OD range: 0 to 4 OD; photometric resolution: 0.001 OD.

Accuracy: < 1% at 2 OD.

Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.

Linearity: ≤ 0.8% at 2.0 OD.

Read Times:

Flying mode (1 flash)

8 s (96), 15 s (384), 28 s (1536)

10 flashes

19 s (96), 57 s (384), 3 min 4 s (1536)

Shaking:

Linear, orbital, and double-orbital with user-definable time and speed

Incubation:

+3°C above ambient up to 45°C

The upper heating plate of the incubation chamber operates at 0.5°C more than the lower plate. This prevents condensation build-up on the lid or sealer

Software:

Multi-user reader control (SMART Control and Voyager) and data analysis software (MARS). Voyager is compatible with CLARIOstar Plus readers from serial number 430-4001.

FDA 21 CFR Part 11 compliance available with SMART Control and MARS.

Integrated fluorophore library.

Dimensions:

Width: 45 cm, depth: 51 cm, height: 40 cm; weight: 32 kg

Included:

PC with software

Stacker for up to 50 plates – continuous loading feature. Only compatible with SMART Control.